Tramadol 50 mg drug

Generic Name: Tramadol 50 mg
Brand Names: ultram 50 mg

Tramadol tablets Mechanism of action

Tramadol 50 mg is often used to treat moderate and severe pain and most types of neuralgia, including trigeminal neuralgia. It is suggested that tramadol could be effective for alleviating symptoms of depression and anxiety because of its action on GABAergic, noradrenergic and serotonergic systems. However, health professionals generally do not suggest use of the drug for treatment of such disorders.

Generic soma Warnings/Precautions

The mode of action of tramadol has yet to be fully understood, but it is believed to work through modulation of the GABAergic, noradrenergic and serotonergic systems. The contribution of non-opioid activity is demonstrated by the analgesic effects of tramadol not being fully antagonised by the opioid receptor antagonist naloxone. Tramadol is marketed as a racemic mixture with a weak affinity for the opioid receptor (approximately 1/6th that of morphine). The (+)-enantiomer is approximately four times more potent than the enantiomer in terms of opioid receptor affinity and 5-HT reuptake, whereas the enantiomer is responsible for noradrenaline reuptake effects (Shipton, 2000). These actions appear to produce a synergistic analgesic effect, with tramadol tablets exhibiting 10-fold higher analgesic activity than tramadol